These variants do not necessarily need to be actors who have already played Spider-Man. Now that Spider-Man: No Way Home has introduced variants of Peter in the form of Tobey Maguire's Peter 2 and Andrew Garfield's Peter 3, the door is open for future variants to appear in the MCU. Furthermore, due to Doctor Strange's spell at the end of No Way Home, he would not remember that Peter Parker is Spider-Man anyway. Having Mysterio return would feel redundant, as he has served his purpose in Peter's story. Jonah Jameson), is a vital plot point in Spider-Man: No Way Home.

The villain's death in Spider-Man: Far From Home is an impactful moment for Peter, and his subsequent deception in convincing the world that Spider-Man killed him (with help from the Daily Bugle's J. Mysterio's death should remain permanent, and Gyllenhaal should return to the franchise as a variant of Peter Parker. Related: Why Spider-Man Has to Make a New Suit at the End of No Way Home Jake Gyllenhaal is also historically connected to Spider-Man, as he was originally lined up to replace Tobey Maguire in Spider-Man 2 after the actor injured his back while filming Spider-Man.

Beck arguably gets the last laugh, however, as he frames Spider-Man for his murder and reveals his secret identity as Peter Parker to the world, leading to the events of Spider-Man: No Way Home. Though he brutally beats Spider-Man, Peter returns and defeats Beck in London, as Mysterio is shot dead by one of his own drones. However, it is revealed that, much like Adrian Toomes (the Vulture), Beck has a messy history with Tony Stark that sees him turn to a life of crime. Gyllenhaal appears in Spider-Man: Far From Home as Mysterio, initially appearing to be an ally to Nick Fury and Peter, helping them defeat the Elementals.

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